Publikationsliste
2023
Habs M, Dingermann T, Bachmeier BE , Eskofier B, Friedrich , Prantl , Emmer J, Langhorst J, Dreischulte T & Koller M (2023). Real World Evidence (RWE) in der Phytotherapie. Z Allg Med (2023) https://doi.org/10.1007/s44266-023-00021-7
2022
Brownlee WJ, Wolf C, Hartung HP, Dingermann T, Anshasi N, Clark RAC, Trojano M, Selmaj K, Uitdehaag BMJ, Tur C, Wuerfel J, Dallmann G, Witte J, Sintzel M, Bobrovnikova O, Cohen JA (2022). Use of follow-on disease-modifying treatments for multiple sclerosis: Consensus recommendations. Multiple Sclerosis Journal, August 2022 https://doi.org/10.1177/13524585221116269
2017
Dingermann T (2017). Biosimilars – neue medikamentöse Optionen. Onkologe 23, 924–928 https://doi.org/10.1007/s00761-017-0296-5
Dingermann T (2017). An important supplement to my article. Zeitschrift fur Rheumatologie 76, 553
Dingermann T (2017). Metamizole : Something to think about. Zeitschrift fur Rheumatologie 76, 377
Fürst R, Zündorf I, Dingermann T (2017). New Knowledge About Old Drugs: The Anti-Inflammatory Properties of Cardiac Glycosides. Planta Medica March 2017, DOI: 10.1055/s-0043-105390
2016
Dingermann T, Scotte F (2016). Biosimilar epoetin zeta: extrapolation of indications and real world utilization experience. Expert Opin Biol Ther. 16:967-74. doi: 10.1080/14712598.2016.1194822.
2015
Bressler B, Dingermann T (2015). Establishing a new marketplace for biologic therapy with biosimilar agents: importance of extrapolation of data. Biosimilars 5:41-48
2014
Zündorf I, Dingermann T (2014). PEGylation – a well-proven strategy for the improvement of recombinant drugs. Pharmazie 69, 323–326
2013
Meyer C, Hofmann J, ... Dingermann T, Klingebiel T, Marschalek R (2013). The MLL recombinome of acute leukemias in 2013. Leukemia doi: 10.1007/
Dingermann T (2013). Das Arzneimittelmarktneuordnungsgesetz (AMNOG) und seine Folgen. Der Internist 17, doi: 10.1007/s00108-013-3247-2
Prelle C, Bursen A, Dingermann T, Marschalek R. (2013). Secondary mutations in t(4;11) leukemia patients. Leukemia 27, 1425-1427, doi: 10.1038/leu.2012.365
2012
Kowarz E, Dingermann T, Marschalek R (2012). Do non-genomically encoded fusion transcripts cause recurrent chromosomal translocations? Cancers 4, 1036-1049; doi:10.3390
Dingermann T, Zündorf I (2012). Overview and classification of approved recombinant drugs. In: Pharmaceutical Biotechnology. Drug Discovery and Clinical Applications, pp 155-178. Oliver Kayser and Heribert Warzecha (eds.). Wiley-Blackwell, ISBN 978-3-527-32994-6
2011
Meyer C, Kowarz E, Yip SF, Wan TS, Chan TK, Dingermann T, Chan LC, Marschalek R. (2011). A complex MLL rearrangement identified five years after initial MDS diagnosis results in out-of-frame fusions without progression to acute leukemia. Cancer Genet.204, 557-562.
Kowarz E, Merkens J, Karas M, Dingermann T, Marschalek R. (2011). Premature transcript termination, trans-splicing and DNA repair: a vicious path to cancer. Am J Blood Res.1, 1-12.
Zimmermann, H., Gerhard, D., Hothorn, L. A., Dingermann, T. (2011). An Alternative to Animal Testing in the Quality Control of Erythropoietin. Pharmeuropa Bio & Scientific Notes 2011-1, 66-80
Pless, B., Oehm, C., Knauer, S., Stauber, R.H., Dingermann, Th., Marschalek, R. (2011). The heterodimerization domains of MLL-FYRN and FYRC--are potential target structures in t(4;11) leukemia. Leukemia. 25, 663-70. Epub 2011 Jan 14.
Benedikt A, Baltruschat S, Scholz B, Bursen A, Arrey TN, Meyer B, Varagnolo L, Müller AM, Karas M, Dingermann T, Marschalek R. (2011). The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures. Leukemia.25, 134-144 Epub 2010 Oct 29
2010
Zimmermann, H., Gerhard, D., Hothorn, L. A., Dingermann, T. (2010). Eine Alternative zum Tierversuch in derQualitätskontrolle von Erythropoietin (Teil 1). Pharmind 72, 708-712
Zimmermann, H., Gerhard, D., Hothorn, L. A., Dingermann, T. (2010). Eine Alternative zum Tierversuch in derQualitätskontrolle von Erythropoietin (Teil 2). Pharmind 72, 884-896
Winckler T, Zündorf I, Dingermann T. (2010). Die Entzifferung der fünften DNA-Base. Das Methylom des Menschen. Pharm unserer Zeit 39, 210-216
Eberle I, Pless B, Braun M, Dingermann Th and Marschalek R (2010). Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells. Nucleic Acids Research 38, 5384-5395
Bursen A, Schwabe K, Rüster B, Henschler R, Ruthardt M, Dingermann T, Marschalek R. (2010). The AF4-MLL fusion protein is capable of inducing ALL in mice without requirement of MLL-AF4. Blood 115, 3570-3579
Zimmermann H, Gerhard D, Dingermann Th, Hothorn LA (2009). Statistical aspects of design and validation of microtitre-plate-based linear and non-linear parallel in vitro bioassays. Biotechnol J. 5, 62-74
2009
Schoser B, Sommer C, Dingermann Th (2009). Morbus Pompe und Morbus Fabry - Seltene therapierbare Stoffwechselerkrankungen mit Bedeutung für den Neurologen. Psychopharmakotherapie 16, 192-197
Wiedenfeld H, Hösch G, Roeder E, Dingermann Th (2009). Lycopsamine and cumambrin B from Eupatorium maculatum. Pharmazie 64, 415-416
Trentin L, Giordan M, Dingermann T, Basso G, Te Kronnie G, Marschalek R (2009). Two independent gene signatures in pediatric t(4;11) acute lymphoblastic leukemia patients. Eur J Haematol. 2009 Jun 25. [Epub ahead of print]
Th. Dingermann (2009). Ähnlich aber nicht gleich: Biosimilars. In: Gut - günstig, Generika: Marktdynamik zum Nutzen unserer Gesundheitsversorgung. Günter Neubauer, Florian Pfister (Hrsg.). Govi-Verlag Pharmazeutischer Verlag GmbH, Eschborn, SS. 63-72
J. Lucas, A. Bilzer, L. Moll, I. Zündorf, Th. Dingermann, L. Eichinger, O. Siol, Th. Winckler (2009). The Carboxy-Terminal Domain of Dictyostelium C-Module-Binding Factor Is an Independent Gene Regulatory Entity. PLoS ONE 4: e5012. doi:10.1371/journal.pone.0005012
Th. Dingermann, A. Vollmar, I. Zündorf (2009). Wenn Harmloses gefährlich wird. Deutsche Apotheker Zeitung 149, 1241-1247 pdf
Meyer C, Kowarz E, Hofmann J, Renneville A, Zuna J, Trka J, Ben Abdelali R, Macintyre E, De Braekeleer E, De Braekeleer M, Delabesse E, de Oliveira MP, Cavé H, Clappier E, van Dongen JJ, Balgobind BV, van den Heuvel-Eibrink MM, Beverloo HB, Panzer-Grümayer R, Teigler-Schlegel A, Harbott J, Kjeldsen E, Schnittger S, Koehl U, Gruhn B, Heidenreich O, Chan LC, Yip SF, Krzywinski M, Eckert C, Möricke A, Schrappe M, Alonso CN, Schäfer BW, Krauter J, Lee DA, Zur Stadt U, Te Kronnie G, Sutton R, Izraeli S, Trakhtenbrot L, Lo Nigro L, Tsaur G, Fechina L, Szczepanski T, Strehl S, Ilencikova D, Molkentin M, Burmeister T, Dingermann T, Klingebiel T, Marschalek R. (2009. New insights to the MLL recombinome of acute leukemias. Leukemia 23, 1490-1499
Theodor Dingermann, Wolfgang Kreis, Horst Rimpler und Ilse Zündorf (2009). Reinhard - Pharmazeutische Biologie 1. 7. Auflage, Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 978-3-8047-2107-4
C. Meyer, A. Brieger, G. Plotz, N. Weber, S. Passmann, Th. Dingermann, S. Zeuzem, J. Trojan, R. Marschalek (2009). An intestinal deletion at 3p21.3 results in the genetic fusion of MLH1 and ITGA9 in a Lynch syndrome family. Clin. Cancer Res. 15, 762-769
2008
Th. Winckler, I. Zündorf, Th. Dingermann (2008). HIV-Impfstoff-Forschung von Rückschlägen gezeichnet. Deutsche Apotheker Zeitung 148, 5380-5387 pdf
Th. Winckler, I. Zündorf, Th. Dingermann (2008). Protein-Tyrosinkinasen als Wirkstoff-Targets. Eine wichtige Gruppe intrazellulärer Regulatoren. Pharm unserer Zeit 37, 370-380.
I. Zündorf, Th. Dingermann (2008). Rekombinante Wirkstoffe: Besonderheiten einer besonderen Wirkstoffklasse. Österreichische Apotheker-Zeitung 62, 1350-1353 pdf
Th. Dingermann (2008). Der Wert des Arzneimittels - Das Arzneimittel im Spannungsfeld zwischen Skandal und Bagatelle: Der leichtfertige Umgang mit einem hohen Gut. Österreichische Apotheker-Zeitung 62, 1212-1217 pdf
M. Metzler, M.S. Staege , L. Harder, D. Mendelova, J. Zuna, E. Fronkova, C. Meyer, T. Flohr, D. Bednarova, J. Harbott, T, Langer, S. Gesk, J. Trka, R. Siebert, Th. Dingermann, R. Marschalek, C. Niemeyer, W. Rascher (2008). Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia. Leukemia, Epub 2008 Mar 13.
Th. Dingermann, I. Zündorf (2008). Diskussion um Tamiflu® - Trügerische Sicherheit oder verantwortungslose Verunsicherung? Deutsche Apotheker Zeitung 148, 66-70
Th. Dingermann (2008). Recombinant therapeutic proteins: Production platforms and challenges. Biotechnol J. 3, 90-97. 2007 Nov 27 Epub ahead of print.
2007
T. Chung, O. Siol, Th. Dingermann, T. Winckler (2007). Protein interactions involved in tRNA gene-specific integration of Dictyostelium non-long terminal repeat retrotransposon TRE5-A. Mol. Cell. Biol. 27, 8492-8501
Th. Dingermann, I. Zündorf (2007). Biosimilars - ähnlich aber nicht gleich. Deutsche Apotheker Zeitung 147, 4186-4192. pdf
Th. Dingermann (2007). Stellungnahme der Kommission "Qualität und Transparenz von Phytopharmaka". Forsch Komplementärmed 14, 180-181. pdf
Th. Dingermann & I. Zündorf (2007). Platzverweis für HI-Virus. Deutsche Apotheker Zeitung 147, 3064-3067 pdf
I. Zündorf, The. Dingermann (2007). Angionese-Inhibitoren der Zukunft. Pharm. unserer Zeit 36, 452-461
Michel Clement, Theo Dingermann, Yali Friedman, Dorothee Heisenberg, Alexander Jahn, Max Keilbach, Sean Safford, Richard Seline (2007). Innovation in the United States and Germany: Case Studies. American Institute for Contemporary German Studies Report 27
A. Lechtken, M. Hörnig, O.Werz, N. Corvey, I. Zündorf, Th. Dingermann, R. Brandes, D. Steinhilber (2007). Extracellular signal-regulated kinase-2 phosphorylates RORalpha4 in vitro. Biochem Biophys Res Commun 358, 890-896,. 2007 May 11
I. Zündorf, A. Vollmar & Th. Dingermann (2007). Grundprinzipien des Immunsystems - Erkennen und angemessen reagieren. Deutsche Apotheker Zeitung 147, 1147-1160 pdf
I. Zündorf, A. Vollmar & Th. Dingermann (2007). Immunsystem aus dem Lot - Gestörtes Gleichgewicht verursacht vielfältige Erkrankungen. Deutsche Apotheker Zeitung 147, 1281-1298 pdf pdf
E. Kowarz, T. Burmeister, L. Lo Nigro, M.W. Jansen, E. Delabesse, T. Klingebiel, Th. Dingermann, & R. Marschalek (2007). Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4.MLL fusion allele. Leukemia 21, 1232-1238, Epub 2007 Apr. 5
A. Gaussmann, T. Wenger, I. Eberle, A. Bursen, S. Bracharz, I Herr, Th. Dingermann, & R. Marschalek (2007).Combined effects of the two reciprocal t(4;11) fusion proteins, MLL•AF4 and AF4•MLL, confer resistance to apoptosis, cell cycling capacity and growth transformation. Oncogene 17, 3352-3363, Epub 2006 Nov.27
C. Meyer, Th. Burmeister, S. Strehl, B. Schneider, D. Hubert, O. Zach, O. Haas, Th. Klingebiel, Th. Dingermann, & R. Marschalek (2007). Spiced MLL fusions: a novel mechanism to generate functional chimeric MLL•MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia. Leukemia, 21, 588-590. Epub 2007 Jan. 25
S. Scharf. J. Zech, A. Bursen, D. Schraets, P.L. Oliver, S. Kliem, E. Pfitzner, E. Gillert, Th. Dingermann, & R. Marschalek (2007). Transcription linked to recombination: a gene-internal promoter coincides with the recombination hotspot II of the human MLL gene. Oncogene 26, 1361-1371, Epub 2006 Sep. 18
I. Zündorf & Th. Dingermann (2007). Grippeimpfstoffe im Zeichen von Epidemie und Pandemie. Deutsche Apotheker Zeitung 147, 38 - 47 pdf
2006
O. Siol, M. Boutliliss, Th. Chung, G. Glöckner, Th. Dingermann & T. Winckler (2006). Role of RNA polymerase III transcription factors in the selection of integration sites by the Dictyostelium non-long terminal repeat retrotransposon TRE5-A. Mol. Cell. Biol. 26, 8242-8251, Epub 2006 Sep 18
O. Rau, M. Wurglics, Th. Dingermann, M. Abdel-Tawab, & M. Schubert-Zslilavecz (2006). Screening of herbal extracts for activation of the human peroxisome proliferator activated receptor. DIE PHARMAZIE, 61, 952-956
P. Schaap, Th. Winckler, M. Nelson, E. Alvarez-Curto, B. Elgie, H. Hagiwara, J. Cavender, A. Milano-Curto, D. E. Rozen, Th. Dingermann, R. Mutzel & S.L. Baldauf (2006). Molecular phylogeny and evolution of morphology in the social amoebas. Science 314, 661-663.
A. Lechtken, I. Zündorf, Th. Dingermann, B. Firlaand, D. Steinhilber (2006).Overexpression, Refolding and Purification of Polyhistidine-Tagged Human Retinoic Acid Related Orphan Receptor RORa4. Protein Expr. Purif. 49, 114-120
O. Rau, M. Wurglics, A. Paulke, J. Zitzkowski, N. Meindl, A. Bock, Th. Dingermann, M. Abdel-Tawab & M. Schubert-Zsilavecz (2006). Carnosic acid and carnosol, phenolic diterpene compounds of the labiate herbs rosemary and sage, are activators of the human peroxisome proliferator-activated receptor gamma. Planta med. 72, 881-887
Th. Dingermann (2006). Demographische Entwicklung und Heilmittelverbrauch. In: F.H. Frimmel & M.B. Müller (Edts). Heil-Lasten - Arzneimittelrückstände in Gewässern. 10. Berliner Kolloquium der Gottlieb Daimler- und Karl Benz-Stiftung. pp. 3 - 28. ISBN 3-540-33637-0 Springer, Berlin, Heidelberg, New York
C. Meyer, E. Kowarz, B. Schneider, C. Oehm, T. Klingebiel, Th. Dingermann, R. Marschalek (2006). Genomic DNA of leukemic patients: target for clinical diagnosis of MLL rearrangements. Biotechnol. J. 1, 656-663
J.J. Gagnier, H. Boon, P. Rochon, D. Moher, J. Barnes, C. Bombardies & CONSORT Group (u.a. Th. Dingermann) (2006). Reporting randomized, controlled trials of herbal interventions: an elaborated CONSORT statement. Ann. Intern. Med.144, 364-367 pdf
Meyer C, Schneider B, Jakob S, Strehl S, Attarbaschi, A, Schnittger, S, Schoch C, Jansen MW, van Dongen JJ, Pieters R, Ennas MG, Angelucci E, Köhl U, Greil J, Griesinger F, Niggli F, Schäfer B, Kemski H, Brady H, Trka J, Lo Nigro L, Biondi A, Stanulla M, Schrappe M, Haas OA, Burmeister T, Repp R, Dingermann Th, Klingebiel T & Marschalek R. (2006). The MLL recombinome of acute leukemia patients. Leukemia 20, 777-784
O. Siol, Th. Dingermann & T. Winckler (2006). The C-module DNA-binding factor mediates expression of the Dictyostelium aggregation-specific adenylyl cyclase ACA. Eukaryot. Cell 5, 658-664
Th. Dingermann & I. Zündorf (2006). Macromolecular Immunosuppressants. Biotechnol. J. 1, 47-57
Th. Dingermann & I. Zündorf (2006). Prädiktive Gendiagnostik in den Händen des Apothekers. Pharm. Ztg. 151, 608-619 pdf
I. Zündorf & Th. Dingermann (2006). Die drohende Influenza-Pandemie. Deutsche Apotheker Zeitung 146, 763-777 pdf
2005
T. Winckler, I. Zündorf & Th. Dingermann (2005). An NIH Model Organism for Biopharmaceutical and Biomedical Research: The Lower Eukaryote Dictyostelium discoideum; in: Modern Biopharmaceuticals - Design, Development and Optimization, J. Knäblein, R.H. Müller (eds), pp. 661-693. Wiley VCH, ISBN 3-527-31184-X.
C. Wihler, S. Schäfer, K. Schmid, E. K. Deemer, G. Münch, M. Bleich, A. E. Busch, T. Dingermann, V. Somoza, J. W. Baynes and J. Huber (2005). Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition. Diabetologia 48, 1645-1653
I. Zündorf, A. Vollmar, Th. Dingermann (2005). Makromolekulare Immunsuppressiva. Pharm. unserer Zeit 34, 283-295.
A. Vollmar, Th. Dingermann, I. Zündorf (2005). Immunologie: Grundlagen und Wirkstoffe. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN3-8047-2189-3
C. Meyer, B. Schneider, M. Reichel, S. Angermueller, S. Strehl, S. Schnittger, C. Schoch, M.W.J.C. J.J. van Dongen, R. Pieters, O.A. Haas, Th. Dingermann, T. Klingebiel, R. Marschalek (2005). Diagnostic tool for the identification of MLL rearrangements including unknown partner genes. Proc. Natl. Acad. Sci. USA 102, 449-454.
Th. Dingermann (2005). Entwicklung und Herstellung monoklonaler Antikörper: Durchbrüche in den ersten 30 Jahren der Entwicklung monoklonaler Antikörper. Arzneim.-Forsch./Drug Res. 55, 692 - 694. pdf
2004
Th. Dingermann, K. Hiller, G. Schneider, I. Zündorf (2004). Arzneidrogen (5. Auflage). Elsevier GmbH, Spektrum Akademischer Verlag, Heidelberg, ISBN 3-8274-1481-4
K. Szafranski, Th. Dingermann, G. Glöckner & Th. Winckler (2004). Template jumping by a Dictyostelium LINE reverse transcriptase created a SINE-like 5S rRNA retropseudogene. Mol. Gen. Genomics 271, 98-102
A. Rohmann, D. Lochmann, J. Weyermann, W.M. Bertling, T. Dingermann & A. Zimmer (2004). Rapid Screening Method for Antisense Oligonucleotides Against Human Growth Factor Receptor p185erb-2. Oligonucleotides 14, 1-9
A. Bursen, S. Moritz, A. Gaussmann, T. Dingermann & R. Marschalek (2004). Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology? Oncogene 23, 6237-6249
T. Winckler, N. Iranfar, P. Beck, I. Jennes, U. Baik, W.F. Loomis & T. Dingermann (2004). CbfA, the C-module DNA-binding factor, plays an essential role in the initiation of Dictyostelium discoideum development. Euk. Cell 3, 1349-1358.
K.M.G. Brand, C. Klein, I. Zündorf, T. Dingermann & W. Knöss (2004). Generation and Characterization of Monoclonal Antibodies to Oleanolic Acid. Planta Med. 70, 986-992.
B. Classen, M. Csávás, A. Borbás, T. Dingermann & I. Zündorf (2004). Monoclonal Antibodies against an Arabinogalactan-Protein from Pressed Juice of Echinacea purpurea. Planta. Med. 70, 861-865.
2003
T.M. Böhme, C. Klein, K. Kreutzmann, M. Linder, Th. Dingermann, G. Dannhardt, E. Mutschler, G. Lambrecht (2003). Structure-activity relationships of dimethindene derivatives as new M2-selective muscarinic receptor antagonists. J. Med. Chem., 46, 856-867
D. Schraets, Th. Dingermann, R. Marschalek (2003). MLL mediated transcriptional gene regulation investigated by gene expression profiling. Oncogene 22, 3655-3668
M. Wurglics, S. Schulte-Löbbert, Th. Dingermann, M. Schubert-Zsilavecz (2003). Rationale und traditionelle Johanniskrautpräparate: Konsequenzen für die Depressionsbehandlung. Deutsche Apotheker Zeitung 143, 1454-1458
Th. Dingermann, D. Loew (2003). Phytopharmakologie: Experimentelle und klinische Pharmakologie pflanzlicher Arzneimittel. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 3-8047-1896-5
A. Lühe, H. Hildebrand, U. Bach, Th. Dingermann, H.J. Ahr (2003). A New Approach to Studying Ochratoxin A (OTA)-Induced Nephrotoxicity: Expression Profiling in Vivo and in Vitro Employing cDNA Microarrays. Toxicol Sci 73, 315-328
Th. Dingermann (2003). Kein Aut-idem bei Phytopharmaka. Geriatrie Journal 7-8/2003, 10-12
J.H. Keller, M. Karas, W.E. Müller, D.A. Volmer, G.P. Eckert, M.A. Tawab, H.H. Blume, Th. Dingermann, M. Schubert-Zsilavecz (2003). Determination of Hyperforin in Mouse Brain by High-Performance LIquid Chromatography/Tandem Mass Spectrometry. Anal. Chem. 75 (22), 6084-6088
K. Fucke, C. Kreienkamp, F. Rezai, S. Steube & Th. Dingermann (2003). Interaktionen mit Phytopharmaka. Prisma 10, 266-27
2002
Th. Dingermann & I. Zündorf (2002). Verheißungen für die Therapie: Embryonale Stammzellen. ÖAZ 56, 760-765
A. Friese, K. Hell-Momeni, I. Zündorf, T. Winckler, T. Dingermann & G. Dannhardt (2002). Synthesis and biological evaluation of cycloalkylidene carboxylic acids as novel effectors of Ras/Raf interaction, J. Med. Chem. 45, 1535-1542
P. Beck, Th. Dingermann & T. Winckler (2002). Transfer RNA gene-targeted retrotransposition of Dictyostelium TRE5-A into a chromosomal UMP synthase gene trap, J. Mol. Biol.318, 273-285
G. Glöckner, L. Eichinger, K. Szafranski, J.A. Pachebat, A.T. Bankier, P.H. Dear, R. Lehmann, C. Baumgart, G. Parra, J.F. Abril, R. Guigó, K. Kumpf, B.Tunggal, the Dictyostelium Genome Sequencing Consortium (u.a. T. Dingermann & T. Winckler), E. Cox, M.A. Quail, M. Platzer, A. Rosenthal & A.A. Noegel (2002). Sequence and analysis of chromosome 2 of Dictyostelium discoideum, Nature 418, 79-85
Th. Dingermann (2002). Gewaltige Verheißungen: Embrynale Stammzellen, Heilsbringer für die Medizin? Forschung Frankfurt 3/2002, 24-30
T. Winckler, T. Dingermann & G. Glöckner (2002). Dictyostelium mobile elements - strategies to amplify in a compact genome (Review), Cell. Mol. Life Sci. 59, 2097-2111
D. Albert, I. Zündorf, Th. Dingermann, W.E. Müller, D. Steinhilber, O. Werz (2002). Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase. Biochemical Pharmacology 64, 1767-1775
K. Beyreuther, H.K. Biesalski, Th. Dingermann, H. Kretzschmar, G. Multhaup, J. Tatzelt, G. Wolfram (2002). Hohenheimer Konsensusgespräch "BSE". Aktuel. Ernaehr. Med. 27, 304-314
K. Dannat, J. Tillner, Th. Winckler, M. Weiß, K. Eger, Th. Dingermann (2003). Effects of medicinal compounds on the differentiation of the eukaryotic microorganism Dictyostelium discoideum: Can this method be used as a screening test for reproductive toxicity in humans? Pharmazie, 58, 204-210
2001
G. Glöckner, K. Szafranski, T. Winckler, T. Dingermann, M. Quail, E. Cox, L. Eichinger, A.A. Noegel & A. Rosenthal (2001). The complex repeats of Dictyostelium discoideum, Genome Res. 11, 585-594
T. Winckler, C. Trautwein, C. Tschepke, C. Neuhäuser, I. Zündorf, G. Vogel & T. Dingermann (2001). Gene function analysis by amber stop codon suppression: CMBF is a nuclear protein that supports growth and development of Dictyostelium amoebae, J. Mol. Biol. 305, 703-714
Th. Dingermann (2001). BSE: Konsequenzen für die Arzneimittelsicherheit. Forschung Frankfurt 3/2001, 27-32
Th. Dingermann (2001). Embryonale Stammzellen: Gewaltige Verheißungen für die Therapie. Pharm.Ztg. 34, 2894-2899
I. Zündorf, Th. Dingermann (2001). Vom Rinder-, Schweine-, Pferde-Insulin zum Humaninsulin: Die biotechnische und gentechnische Insulin-Herstellung. Pharm. unserer Zeit 30, 27-32
U. Hentschel, I. Zündorf, T. Dingermann & T. Winckler (2001). On the problem of establishing the subcellular localization of Dictyostelium retrotransposon TRE5-A proteins by biochemical analysis of nuclear extracts, Anal. Biochem. 296, 83-9
I. Zündorf, Th. Dingermann (2001). Struktur des HI-Virus. Pharm. unserer Zeit 30, 203 - 207
E. Reinhard, Th. Dingermann, W. Kreis, H. Rimpler (2001). Pharmazeutische Biologie: Die biologischen Grundlagen für Studium und Praxis. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 3-8047-1785-3
K.M. Pang, Th. Dingermann & D.A. Knecht (2001). Regulated expression of myosin II heavy chain and RacB using an inducible tRNA suppressor gene, Gene 277, 187-197
Th. Dingermann, E. Giger & M.H. Kreuter (2001). Black Cohosh. Food Processing Japan 36, 60-62
2000
Dingermann, Th. (Hrsg.) unter Mitarbeit der Expertenkommission BARMER/BPI (2000). Transparenzkrierien für pflanzliche, homöopathische und anthroposophische Arzneimittel. Expertenvotum zur Vorbereitung eines Modellvorhabens nach §§ 63 - 65 SGB V zur Förderung der Rationalität der Verordnung pflanzlicher, homöopathischer und anthroposophischer Arzneimittel. Karger GmbH, Basel, Freiburg, Paris.
Dingermann, Th. (2000). Wie gefährlich ist die Gentechnik? In: Pharmazeutische Biotechnologie. Kompendium für Forschung und Praxis, O. Kayser & H. Müller (Hrsg.). Wissenschaftliche Verlagsgesellschaft, Stuttgart, pp. 369 - 384.
Zündorf, I., and Dingermann, Th. (2000). Neue gentechnisch hergestellte Arzneimittel. Pharm. unserer Zeit 29, 167 - 173.
Schlitzer, M., Sattler, I., Friese, A., Zündorf, I., and Dingermann, Th. (2000). Synthesis of 4-(acylaminomethyl)benzamides and their evaluation as potential anticancer agents. Anticancer Res. 20, 1723 - 1726
Dingermann, Th., and Morck, H. (2000). Gezielte Therapie mit Hightech-Arzneimitteln. Pharm. Ztg. 49, 4187 - 4190
S. Henke, A. Rohmann, W. M. Bertling, T. Dingermann, and A. Zimmer (2000). Enhanced in vitro oligonucleotide and plasmid DNA transport by VP1 virus-like particles. Pharmaceutical Research 17, 1062-1070.
1999
Wolf, H.-T., van den Berg, Th., Czygan, F.-C., Mosandl, A., Winckler, Th., Zündorf, I., and Dingermann, Th. (1999). Identification of Melissa officinalis subspecies by DNA fingerprinting. Planta Med. 65, 83-85
Wolf, H.-T., Zündorf, I., Winckler, Th., Bauer, R., and Dingermann, Th. (1999). Characterization of Echinacea species and detection of possible adulterations by RAPD analysis. Planta Med. 65, 773-774
Horn, J., Dietz-Schmidt, A., Zündorf, I., Garin, J., Dingermann, T., and Winckler, T. (1999). A Dictyostelium protein binds to distinct oligo(dA)•oligo(dT) DNA sequences in the C-module of the retrotransposable element DRE. Eur. J. Biochem. 265, 441-448
Szafranski, K., Glöckner, G., Dingermann, T., Dannat, K., Noegel, A.A., Eichinger, L., Rosenthal, A., and Winckler, T. (1999). Non-LTR retroelements with unique integration preferences downstream of Dictyostelium discoideum transfer RNA genes. Mol. Gen. Genet. 262, 772-780
Dingermann, Th. (1999). Stoffproduktion durch gentechnisch veränderte Organismen. In: Arzneidrogen, G. Schneider & K. Hiller (Hrsg.), Spektrum Aksdemischer Verlag, Heidelberg, Berlin, pp. 55 - 66.
Dingermann, Th. (1999). Essential similarity bei Phytopharmaka. In: Phytopharmaka V: Forschung und klinische Anwendung, D. Loew, H. Blume & Th. Dingermann (eds), Steinkopff Verlag, Darmstadt, pp. 27-33
Dingermann, Th., Zündorf, I. (1999). Gentechnik - Biotechnik . Lehrbuch und Kompendium für Studium und Praxis. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 3-8047-1597-4
1998
Tillner, J., Nau, H., Winckler, Th. and Dingermann, Th. (1998). Evaluation of the teratogenic potential of valproic acid analogues in the eucaryotic microorganism Dictyostelium discoideum . Toxicol. In Vitro 12, 463-469
Winckler, Th., Tschepke, Ch., de Hostos, E.L., Jendretzke, A. and Dingermann, Th. (1998). Tdd-3, a transfer RNA gene-associated poly(A) retrotransposon in the genome of Dictyostelium discoideum. Mol. Gen. Genet. 257, 655-661
Zündorf, I., Wiedenfeld, H., Röder, E. and Dingermann, Th. (1998). Generation and Characterization of Monoclonal Antibodies against the Pyrrolizidine Alkaloid Retrorsine. Planta Med. 64, 259-263
Tillner, J., and Dingermann, Th. (1998). Retinoide und Embryonalentwicklung: Molekulare Mechanismen der Teratogenität. Deutsche Apotheker Zeitung 138, 704-710
Dingermann, Th., and Zündorf, I. (1998). Das Immunsystem: Ziel und Quelle von Arzneistoffen. Teil 1: Komponenten des Immunsystem. Prisma 5, 28
Dingermann, Th., and Zündorf, I. (1998). Das Immunsystem: Ziel und Quelle von Arzneistoffen. Teil 2: Arzneistoffe mit Wirkung auf das Immunsystem. Prisma 5, 108-113
Dingermann, Th. (1998). Gentechnologie und Arzneimittel. Internist. Prax. 38, 711-726
Winckler, Th. (1998). Retrotransposable elements in the Dictyostelium discoideum genome. Cell. Mol. Life Sci. 54, 383-393
Van Rensen, I., Blume, H., Ihrig, M., Morck, H., Dingermann, Th., and Veit, M. (1998). Bewertung von Phytopharmaka in der Apothekenpraxis. Pharm. Z. 143, 561-569
Veit, M., van Rensen, I., Blume, H., Ihrig, M., Morck, H., and Dingermann, Th. (1998). Bewertung von Phytopharmaka in der Therapie der BPH. Pharm. Z. 143, 1905- 1927
Zündorf, I, and Dingermann, Th. (1998). Gentechnologie und Arzneimittel. PharmuZ 27, 223-232
Dingermann, Th. (1998). Gentechnisch hergestellte Arzneimittel. Apotheke und Krankenhaus 14, 78-84
Dingermann, Th. (1998). Gentechnologie und Arzneimittel. tägl. prax. 39, 711-726
Dingermann, Th. (1998). Pharmazeutische Qualität von Phytopharmaka. In: Phytotherapie bei Störungen und Erkrankungen des Nervensystems, S. Chrubasik & M. Wink (eds), Verlag M. Rheinheimer, Ludwigshafen, pp. 15-23
1997
Dingermann, Th. (1997). Gentechnisch hergestellte Arzneistoffe: Eine neue Wirkstoffklasse mit neuen Herausforderungen an die Analytik und Bewertung. Pharm. Ind. 59, 348-351
Bukenberger, M., Horn, J., Dingermann, Th., Dottin, R.P. and Winckler, Th. (1997). Molecular cloning of a cDNA encoding the nucleosome core histone H3 from Dictyostelium discoideum by genetic screening in yeast. BBA 1352, 85-90
Zündorf, I., and Dingermann, Th. (1997). Bewertung der Qualität von Phytopharmaka. Deutsche Apotheker Zeitung 137, 3107-3118.
Dingermann, Th. (1997). Wie gefährlich ist die Gentechnik? PharmuZ 26, 192 - 198
Dingermann, Th. (1997). Phytopharmaka in der Dermatologie. Österreichische Apotheker Zeitung 51, 783-786
Morrison, A., Marschalek, R., Dingermann, Th., and Harwood, A.J. (1997). A novel, negative selectable marker for gene disruption in Dictyostelium. Gene 202, 171 - 176
1996
Hösch G., Wiedenfeld, H., Dingermann, Th., and Röder, E. (1996). A new HPLC-method for the simultaneous quantitative analysis of pyrrolizidine alkaloids and their N-oxides in Senecio leucophyllus. Phytochemical Anal. 7, 284-288
Dingermann, Th. (1996). Gentechnisch modifizierte Nahrung. Was kommt auf uns zu? Praxismagazin med. 2/96, 52-54
Li, Z., Sommer, A., Dingermann, Th., and Noe, C.R. (1996). Molecular cloning and sequence analysis of a cysteine protease inhibitor of Sorgum bicolor seedlings. Mol. Gen. Genet. 251, 499-502
Dingermann, Th. (1996).Bovine Spongiforme Encephalopathie. Deutsche Apotheker Zeitung 136, 165
Geier, A., Horn, J., Dingermann, Th., and Winckler, Th. (1996). A nuclear protein factor binds specifically to the 3'-regulatory module of the long-interspersed-nuclear-element-like Dictyostelium repetitive element. Eur. J. Biochem., 241, 70-76
Toto, T., Adams, E.F., Fahlbusch, R., Dingermann, Th., Werner, H. (1996). Autocrine growth stimulation of human meningioma cells by platelet-derived growth factor. J Neurosurgery 84, 852-858
Dingermann, Th. (1996). BSE: Konsequenzen für die Arzneimittelsicherheit I. Bioforum 7-8, 298-301
Dingermann, Th. (1996). BSE: Konsequenzen für die Arzneimittelsicherheit II. Bioforum 9, 366-368
Tillner, J., Winckler, Th., and Dingermann, Th. (1996). Developmentally regulated promoters from Dictyostelium discoideum as molecular markers for testing potential teratogens. Pharmazie 51, 902-906
Dingermann, Th. (1996). Gentechnologie. In: Lehrbuch der Pharmazeutischen Biologie, R. Hänsel, J. Hölzl, (Hrsg.)., Springer-Verlag, Berlin, Heidelberg, New York, pp. 454 - 477
1995
Kuspa, A., Dingermann, Th., and Nellen, W. (1995). Analysis of gene function in Dictyostelium. Experientia 51, 1116-1123
Voith, G., and Dingermann, Th. (1995). Expression of the human muscarinic receptor gene m2 in Dictyostelium discoideum. Nature Biotechnology 13, 1225-1229
Voith, G., and Dingermann, Th. (1995). Expression of CSA-hm2 fusion in Dictyostelium discoideum under the control of the Dictyostelium ras promoter reveals functional muscarinic receptors. Pharmazie 50, 758-762
Dingermann, Th. (1995). Gentechnische Modifikationen von Nahrungs- und Arzneipflanzen. Bioforum 18, 252-257
Dingermann, Th. (1995). Phytopharmaka im Alter. Pharmazeutische Zeitung 23, 9 -16
1994
Schumann, G., Zündorf, I., Hofmann, J., Marschalek, R., and Dingermann, Th. (1994). Internally located and oppositely oriented Pol II promoters direct convergent transcription of the retrotransposon DRE from Dictyostelium discoideum. Mol. Cell. Biol. 14, 3074-3084
Bukenberger, M., Dingermann, T., Meissner, W., Seifart, K.H., and Winckler, Th. (1994). Isolation of transcription factor IIIC from Dictyostelium discoideum. Eur. J. Biochem. 220, 839-846
Dingermann, Th. (1994). Gentechnologie in der Pflanzenphysiologie: Eine Herausforderung für Wissenschaftler und Verbraucher. Österreichische Apotheker Zeitung 48, 389-395
Schumann, G., Zündorf, I., Schmidt, A., Marschalek, R., and Dingermann, Th. (1994). Characterization of transcripts from the Dictyostelium discoideum retrotransposable genetic element DRE. Pharmazie 49, 923-925
Tillner, J., Winckler, Th., and Dingermann, Th. (1994). A simple cytotoxicity assay using the eucaryotic microorgamism Dictyostelium discoideum. Pharmazie 49, 759-761
Adams, E.F., Dingermann, Th., Fahlbusch, R., Rafferty, B., Toto, T., Werner, H. (1994). Secretion of interleukin-6 by human meningioma cells: Possible autocrine inhibitory regulation of neoplastic cell growth. J Neurosurgery 81, 394-401
Dingermann, Th. (1994). Gentechnisch modifizierte Nahrung: Was kommt auf uns zu? Pharm. Z. 139, 3901-3908
Dingermann, Th. (1994). Molekularbiologie und Pharmazie. Deutsche Apotheker Zeitung 134, 4353-4360
Dingermann, Th. (1994). Gentechnische Herstellung von Insulin. Deutsche Apotheker Zeitung 134, 177-189
1993
Dingermannn, Th. (1993). Funktionelle Rezeptorexpression in Dictyostelium discoideum. Patentschrift P 43 13 933.7
Rizzuto, R., Sandoná, D., Brini, M., Marschalek, R., Dingermann, Th., and Bisson, R. (1993). Structure of the promoter region of the gene encoding cytochrome c oxidase subunit V in Dictyostelium. Eur. J. Biochem. 211, 411-414
Hofmann, J., Schumann, G., Marschalek, R., Hanenkamp, A., Bukenberger, M., Winckler, Th., and Dingermann, Th. (1993). The Dictyostelium discoideum 5S rDNA is organized in the same transcriptional orientation as the other rDNAs. Biochem. Biophys. Res. Comm. 191, 558-564
Hoja, U., Hofmann, J., Marschalek, R., and Dingermann, Th. (1993). Nucleotide sequence of a Dictyostelium discoideum gene encoding a protein homologous to the yeast ribosomal protein S31. Biochem. Biophys. Res. Comm. 190, 134-139
Marschalek, R., Hofmann, J., Schumann, G., Bach, M., and Dingermann, Th. (1993). Different organization of the retrotransposon DRE in NC4 derived strains and in other wild-type Dictyostelium discoideum strains. Eur. J. Biochem. 217, 627-631
Zündorf, I., Reinke, M, and Dingermann, Th. (1993). Expression of antibody fragments directed against Prostaglandin E2 on the surface of filamentous phage. Pharm. Pharmacol. Lett. 3, 32-35
Dingermann, Th. (1993). Kann die Molekularbiologie die Pharmazie bereichern? Arch. Pharm.326, 845
Dingermann, Th. (1993). Gentechnologie - Können wir auf sie verzichten? PTA heute 7, 652-660
Dingermann, Th. (1993). Nukleinsäuren als potentielle Pharmaka. Deutsche Apotheker Zeitung 133, 4209-4223
1992
Rau, D., Tittelbach, H., Dingermann, Th., and Gebhart, E. (1992). Trisomy 7 in short-term cultures of colorectal adenocarcinomas Genes, Chromsomes and Cancer. 4, 104-105
Marschalek, R., Hofmann, J., Schumann, G., Gösseringer, R., and Dingermann, Th. (1992). Structure of DRE, a retrotransposable element which integrates with position-specificity upstream of Dictyostelium discoideum tRNA genes. Mol. Cell. Biol. 12, 229-239
Dingermann, Th., Frank-Stoll, U., Werner, H., Wissmann, A., Hillen, W., Jacquet, M., and Marschalek, R. (1992). RNA polymerase III catalyzed transcription can be regulated in Saccharomyces cerevisiae by the bacterial tetracycline repressor-operator system. EMBO J. 11, 1487-1492
Dingermann, Th., Werner, H., Schütz, A., Zündorf, I., Nerke, K., Knecht, D., and Marschalek, R. (1992). Establishment of a system for conditional gene expression using an inducible tRNA suppressor gene. Mol. Cell. Biol. 12, 4038-4045
Dingermann, Th., Leipold, A., Landgraf, S. Gebhart, E., Tulusan A.H. and Kersten, W. (1992). Over-expression of cellular oncogenes in cystadeno carcinomas of the ovary. Intern. J. Oncol. 1, 347-352
Rau, D., Neubauer, S., Köster, A., Giedl, J., Sachse, R., Landgraf, S., Leipold, A., Dingermann, Th., and Gebhart, E. (1992). Cytogenetic, oncogenetic and histopathologic characteristics of colorectal carcinomas with 17p abnormalities. Human Genet. 89, 64-68
Gebhart, E., Rau, D., Neubauer, S., and Dingermann, Th. (1992). Chromosome 1 in human colorectal tumors. Hum. Genet. 90, 188-190
Dingermann, Th. (1992). Vom Gewächshaus über den Fermenter in den Tierstall: Neue Wege in der Pharmazeutischen Biologie. Deutsche Apotheker Zeitung 23, 1216-122
Zündorf, I. and Dingermann, Th. (1992). Molekularbiologie: Methoden und Konzepte. Deutsche Apotheker Zeitung 26, 1373-1381
Dingermann, Th. (1992). Tumorentstehung und neue Therapiemöglichkeiten. Med. Mo. Pharm. 11, 322-332
Marschalek, R., Hofmann, J., Schumann, G., and Dingermann, Th. (1992). Two distinct subforms of the retrotransposable DRE element in NC4 strains of Dictyostelium discoideum. Nucl. Acids Res. 20, 6247-6252
1991
Kalpaxis, D., Zündorf, I., Werner, H., Reindl, N., Boy-Marcotte, E., Jacquet, M., and Dingermann, Th. (1991). Positive selection for Dictyostelium discoideum mutants lacking UMP synthase activity based on resistance to 5-fluoroorotic acid. Mol. Gen. Genet. 225, 492-500
Köster, A., Landgraf, S., Leipold, A., Sachse, R., Gebhart, E., Tulusan, A.H., Rónay, R, Schmidt, C., and Dingermann, Th. (1991). Expression of oncogenes in human breast cancer specimens. Anticancer Res. 11, 193-202
Dingermann, Th., Troidl, E.-M., Bröker, M., and Nerke, K. (1991). Expression of human antithrombin III in the cellular slime mold Dictyostelium discoideum. Appl. Microbiol. Biotechnol. 35, 496-50
Bukenberger, M., Marschalek, R., Salzburger, W., and Dingermann, Th. (1991). Nuclear factors which bind to Dictyostelium discoideumtransfer RNA genes. Current Genetics 20, 129-135
Dingermannn, Th. (1991). Suppressor-tRNA-Genstranskriptionssysteme Patentschrift P 41 03 952.1
Hofmann, J., Schumann, G., Borschet, G., Gösseringer, R., Bach, M., Bertling, W., Marschalek, R., and Dingermann, Th. (1991). Transfer RNA genes from Dictyostelium discoideum are frequently associated with repetitive elements and contain consensus boxes in their 5'- and 3'-flanking regions. J. Mol. Biol. 222, 537-552
Rau, D., Köster, A., Tittelbach, H., Sachse, R., Landgraf, S., Neubauer, S., Giedl, J., Dingermann, Th., and Gebhart, E. (1991).Chromosome and oncogene studies in human rectal and colon carcinomas. Anticancer Res. 11, 1477-1484
Marschalek, R., and Dingermann, Th. (1991). Structure, organization and function of transfer RNA genes from the cellular slime mold Dictyostelium discoideum. In Advances in Gene Technology Vol. 2. P.J. Greenaway (ed).JAI Press Inc., Greenwich, 103-143
1990
Marschalek, R., Kalpaxis, D., and Dingermann, Th. (1990). Temperature sensitive synthesis of transfer RNAs in vivo in Saccharomyces cerevisiae. EMBO J. 9, 1253-1258
Kalpaxis, D., Werner, H., Boy-Marcotte, E., Jacquet, M., and Dingermann, Th. (1990). Positive selection for Dictyostelium mutants lacking uridine monophosphate synthase activity based on resistance to 5-fluoro-orotic acid. Dev. Genet. 11, 396-402
Dingermann, Th., Reindl, N., Brechner, Th., Werner, H, and Nerke, K. (1990). Nonsense suppression in Dictyostelium discoideum. Dev. Genet. 11, 410-417
Marschalek, R., Borschet, G., and Dingermann, Th. (1990). Genomic organization of the transposable element Tdd-3 from Dictyostelium discoideum. Nucl. Acids Res. 18, 5751-5757
1989
Marschalek, R., Amon-Böhm, E., Stoerker, J., Klages, S., Fleckenstein, B., and Dingermann, Th. (1989). CMER, an RNA encoded by the human cytomegalovirus is most likely transcribed by RNA polymerase III. Nucl. Acids Res 17, 631-643.
Dingermann, Th., Brechner, Th., Marschalek, R., Amon-Böhm, E., and Welker, D. (1989). tRNAGlu(GAA) genes from the cellular slime mold Dictyostelium discoideum. DNA 8, 193-204 ( Abstract )
Marschalek, R., Brechner, Th., Amon-Böhm, E., and Dingermann, Th. (1989). tRNA genes: Landmarks for integration of mobile genetic elements in Dictyostelium discoideum. Science 244, 1493-1496 ( Abstract )
Gebhart, E., and Dingermann, Th. (1989). Molecular biology of human colorectal cancer. Cancer Bull. 41, 318-324
Dingermann, Th., Reindl, N., Werner, H., Hildebrandt, M., Nellen, W., Harwood, A. Williams, J., and Nerke, K. (1989). Optimization and in situ detection of Escherichia coli ß-galactosidase gene expression in Dictyostelium discoideum. Gene 85, 353-362
Michelsen, U., Bösl, M., Dingermann, Th., and Kersten, H. (1989). The tyrT locus of Eschericha coli exhibits a regulatory function for glycine metabolism. J. Bact. 171, 5987-5994
Dingermann, Th. (1989). Structure, organization and expression of eukaryotic transfer RNA genes Mol. Gen. (Life Sci. Adv.) 8, 57-64.
1988
Dingermann, Th., Nerke, K., Blöcker, H., and Frank, R. (1988). Structural requirements for synthesis of tRNATrp from Dictyostelium discoideum in yeast Biochimie 70, 711-719.
Von Heimendahl, G., Gebhart, E., and Dingermann, Th. (1988). Proto-oncogene activation in surgical specimens of rectal carcinoma. Anticancer Res. 8, 805-812.
Marschalek, R and Dingermann, Th. (1988). Identification of a protein factor binding to the 5'-flanking region of a tRNA gene and being involved in modulation of tRNA gene transcription in vivo in Saccharomyces cerevisiae. Nucl. Acids Res. 16, 6737-6752.
Dingermann, Th., Amon-Böhm, E., Bertling, W., Marschalek, R., and Nerke, K. (1988). The gene family of nonallelic tRNAVal(GUU) genes from the cellular slime mold Dictyostelium discoideum. Gene 73, 373-384
1987
Bertling, W., Kaiserwerth, M., and Dingermann, Th. (1987). Comparative study of 5´-flanking sequences of eukaryotic tRNA genes: possible functional implications. Int. J. Biol. Macromol. 9, 63-70.
Dingermann, Th., Amon E., Williams, K.L., and Welker, D.L. (1987). Chromosomal mapping of tRNA genes from Dictyostelium discoideum. Mol. Gen. Gene 207, 176-187.
Dingermann, Th., and Nerke, K. (1987). Primer extension analysis of tRNA gene transcripts synthesized in vitro and in vivo Analytical Biochem. 162, 466-475.
Dingermann, Th., Nerke, K., and Marschalek, R. (1987). Influence of different 5´-flanking sequences of tRNA genes on their in vivo transcription efficiencies. Eur. J. Biochem. 170, 217-224.
Dingermann, Th., Amon-Böhm, E., Bertling, W., Marschalek, R., and Nerke, K. (1987). Structure, genomic organization and developmental expression of members of a tRNAVal(GUU) gene family of the cellular slime mold Dictyostelium discoideum. Mol. Gen. (Life Sci. Adv.) 6, 152-159.
1986
Dingermann, Th., Bertling, W., Brechner, Th., Nerke, K., Peffley, D.M., and Sogin, M.L. (1986). Structure of two trna genes from Dictyostelium discoideum. Nucl. Acids Res. 14, 1127.
1985
Frendewey, D., Dingermann, Th., Cooley, L. and Söll, D. (1985). Processing of precursor tRNAs in Drosophila: processing of the 3´ end involves an endonucleolytic cleavage and occures after 5´ end maturation. J. Biol. Chem. 260, 449-454.
Dingermann, Th., Bertling, W., Pistel, F. and Amon, E. (1985). Characterisation of a Dictyostelium discoideum DNA fragment coding for a putative tRNAVal (GUU) gene: evidence for a single transcription unit consisting of two overlapping class III genes. Eur. J. Biochem. 146, 449-458.
Thorbjarnardóttir, S., Uemura, H., Dingermann, Th., Rafnar, Th., Thorsteinsdóttir, S., Söll, D., and Eggertsson, G. (1985). Escherichia coli supH suppressor: temperature-sensitive missens suppression caused by an anticodon change in tRNASer(2). J. Bact. 161, 207-211.
Thorbjarnardóttir, S., Dingermann, Th., Rafnar, Th., Andersson, O.S., Söll, D., and Eggertsson, G. (1985). Leucine tRNA family of Escherichia coli: nucleotide sequence of the supP(am) suppressor gene. J. Bact. 161, 219-222.
1984
Schaack, J., Sharp, S., Dingermann, Th., Burke, D.J., Cooley, L. and Söll, D. (1984). The extend of a eucaryotic tRNA gGene: 5´- and 3´-flanking sequence dependence for transcription and stable complex formation. J. Biol. Chem. 259, 1461-1467.
1983
Sharp, S., Dingermann, Th., Schaack, J., DeFranco, D. and Söll, D. (1983). Transcription of eucaryotic tRNA genes in vitro: I. Analysis of control regions using a competition assay. J. Biol. Chem. 258, 2440-2446.
Schaack, J., Sharp, S., Dingermann, Th. and Söll, D. (1983). Transcription of eucaryotic tRNA genes in vitro: II. Formation of stable complexes. J. Biol. Chem. 258, 2447-2453.
Sharp, S., Dingermann, Th., Schaack, J., Scharp, J.A., Burke, D.J., DeRobertis, E.M. and Söll, D. (1983). Each element of the Drosophila tRNAArg gene split promoter directs transcription in Xenopus oocytes. Nucl. Acids Res. 11, 8677-8690.
Sharp, S., Cooley, L., DeFranco, D., Dingermann, Th. and Söll, D. (1983). Organisation and expression of tRNA genes in Drosophila melanogaster. In Recent Results in Cancer Research Vol. 84, G. Nass (ed.), Springer Verlag Berlin, pp. 1-14.
Dingermann, Th., Sharp, S., Schaack, J. and Söll, D. (1983). Stable transcription complex formation of eucaryotic tRNA genes is dependent on a limited separation of the two intragenic control regions. J. Biol. Chem. 258, 10395-10402.
1982
Dingermann, Th., Sharp, S., Schaack, J., DeFranco, D., Johnson, D.L., Cooley, L. and Söll, D. (1982). The in vitro transcription of Drosophila tRNA genes. In: Gene Regulation, UCLA Symposia on Molecular and Cellular Biology, Vol. XXVI, Bert O´Maley and C. Fred Fox (eds.), Academic Press, New York, NY., pp. 219-234.
Dingermann, Th., Burke, B.J., Sharp, S., Schaack, J. and Söll, D. (1982). The 5´ flanking sequences of Drosophila tRNAArg genes control their in vitro transcription in a Drosophila cell extract. J. Biol. Chem. 257, 14738-14744.
DeFranco, D., Dingermann, Th., Johnson, D.L., Sharp, S. and Söll, D. (1982). Eukaryotic tRNA gene transcription is controlled by signals within and outside the mature coding sequence. In: Primary and Tertiary Structure of Nucleic Acids and Cancer Research, M.Miwa et al. (eds.), Japan Sci. Soc. Press, Tokyo, pp. 63-72.
Sharp, S., Dingermann, Th. and Söll, D. (1982). The minimum intragenic sequences required for promotion of eucaryotic tRNA gene transcription. Nucl. Acids. Res. 10, 5393-5406.
1981
Dingermann, Th., Sharp, S., Appel, B., DeFranco, D., Mount, S., Heiermann, R., Pongs, O. and Söll, D. (1981). Transcription of cloned tRNA and 5S RNA genes in a Drosophila cell free extract. Nucl. Acids Res. 9, 3907-3918
Dingermann, Th., Ogilvie, A., Pistel, F., Mühlhofer, W. and Kersten, H. (1981). Reduced aminoacylation of asparagine-transfer RNA early in the developmental cycle of Dictyostelium discoideum: modification pattern and possible significance of the uncharged isoacceptor tRNAAsn(3). Hoppe Seyler´s Z. Physiol. Chem. 362, 763-773.
Sharp, S., DeFranco, D., Dingermann, Th., Farrel, P. and Söll, D. (1981). Internal control regions for transcription of eucaryotic tRNA genes. Proc. Natl. Acad. Sci. U.S.A. 78, 6657-6661.
1980
Dingermann, Th., Pistel, F. and Kersten, H. (1980). Functional role of ribothymidine in transfer RNA. Eur. J. Biochem. 104, 33-40.
1979
Dingermann, Th., Mach, M. and Kersten, H. (1979). Synthesis of transfer ribonucleic acids with uridine or 2´-O-methylribothymidine at position 54 in developing Dictyostelium discoideum. J. Gen. Microbiol. 115, 223-232.
1977
Dingermann, Th., Schmidt, W. and Kersten, H. (1977). Modified bases in tRNA of Dictyostelium discoideum: alterations in the ribothymidine content during development. FEBS Letters 80, 205-208.