AK Windbergs
Arbeitskreis Windbergs
Windbergs Lab
We’re an interdisciplinary team of Pharmacists, Chemists, Biologists and other natural sciences with the common aim of developing novel therapeutics in the context of wound healing, infection, inflammation and tissue regeneration.
To find out more about our research, visit our website on WindbergsLab.de.
Publications
Kielholz T, Rohde F, Jung N, Windbergs M. Bacteriophage-loaded functional nanofibers for treatment of P. aeruginosa and S. aureus wound infections. Sci Rep. 2023 May 23;13(1):8330. doi: 10.1038/s41598-023-35364-5. PMID: 37221194; PMCID: PMC10205809.
Wächter J, Vestweber PK, Jung N, Windbergs M. Imitating the microenvironment of native biofilms using nanofibrous scaffolds to emulate chronic wound infections. J Mater Chem B. 2023 Apr 5;11(14):3212-3225. doi: 10.1039/d2tb02700c. PMID: 36951960.
Rohde F, Walther M, Baur F, Windbergs M. A Dual-Function Electrospun Matrix for the Prevention of Herpes Simplex Virus-1 Infections after Corneal Transplantation. Adv NanoBiomed Res. 2023, 3(3):2699-9307. doi: 10.1002/anbr.202200098.
Dos Santos J, Balbinot GS, Buchner S, Collares FM, Windbergs M, Deon M, Beck RCR. 3D printed matrix solid forms: Can the drug solubility and dose customisation affect their controlled release behaviour? Int J Pharm X. 2022 Dec 23;5:100153. doi: 10.1016/j.ijpx.2022.100153. PMID: 36632070; PMCID: PMC9827047.
Brettner FEB, Schreiner J, Vogel-Kindgen S, Windbergs M. Engineered Self-Assembly of Amphiphilic Cyclodextrin Conjugates for Drug Encapsulation. ACS Biomater Sci Eng. 2022 Dec 23. doi: 10.1021/acsbiomaterials.2c01023. Epub ahead of print. PMID: 36562386.
Walther M, Vestweber PK, Kühn S, Rieger U, Schäfer J, Münch C, Vogel-Kindgen S, Planz V, Windbergs M. Bioactive Insulin-Loaded Electrospun Wound Dressings for Localized Drug Delivery and Stimulation of Protein Expression Associated with Wound Healing. Mol Pharm. 2023 Jan 2;20(1):241-254. doi: 10.1021/acs.molpharmaceut.2c00610. Epub 2022 Dec 20. PMID: 36538353.
Kielholz T, Walther M, Jung N, Windbergs M. Electrospun fibers loaded with antimicrobial peptides for treatment of wound infections. Eur J Pharm Biopharm. 2022 Oct;179:246-255. doi: 10.1016/j.ejpb.2022.09.014. Epub 2022 Sep 20. PMID: 36150615.
Schwickert M, Fischer TR, Zimmermann RA, Hoba SN, Meidner JL, Weber M, Weber M, Stark MM, Koch J, Jung N, Kersten C, Windbergs M, Lyko F, Helm M, Schirmeister T. Discovery of Inhibitors of DNA Methyltransferase 2, an Epitranscriptomic Modulator and Potential Target for Cancer Treatment. J Med Chem. 2022 Jul 28;65(14):9750-9788. doi: 10.1021/acs.jmedchem.2c00388. Epub 2022 Jul 18. PMID: 35849534.
Kaiser P, Wächter J, Windbergs M. Therapy of infected wounds: overcoming clinical challenges by advanced drug delivery systems. Drug Deliv Transl Res. 2021 Aug;11(4):1545-1567. doi: 10.1007/s13346-021-00932-7. Epub 2021 Feb 20. PMID: 33611768; PMCID: PMC8236057.
Rohde F, Danz K, Jung N, Wagner S, Windbergs M. Electrospun Scaffolds as Cell Culture Substrates for the Cultivation of an In Vitro Blood-Brain Barrier Model Using Human Induced Pluripotent Stem Cells. Pharmaceutics. 2022 Jun 20;14(6):1308. doi: 10.3390/pharmaceutics14061308. PMID: 35745880; PMCID: PMC9231001.
Friedl JD, Walther M, Vestweber PK, Wächter J, Knoll P, Jörgensen AM, Bernkop-Schnürch A, Windbergs M. SEDDS-loaded mucoadhesive fiber patches for advanced oromucosal delivery of poorly soluble drugs. J Contr Rel. 2022 Mai; Vol 348:692-705. doi: 10.1016/j.jconrel.2022.06.023.
Jung N, Namjoshi S, Mohammed Y, Grice JE, Benson HAE, Raney SG, Roberts MS, Windbergs M. Application of Confocal Raman Microscopy for the Characterization of Topical Semisolid Formulations and their Penetration into Human Skin Ex Vivo. Pharm Res. 2022 May;39(5):935-948. doi: 10.1007/s11095-022-03245-7. Epub 2022 Apr 11. PMID: 35411509; PMCID: PMC9160154.
Löblein J, Lorson T, Komma M, Kielholz T, Windbergs M, Dalton PD, Luxenhofer R. An initiator- and catalyst-free hydrogel coating process for 3D printed medical-grade poly(ε-caprolactone). Beilstein J Org Chem. 2021 Aug 19;17:2095-2101. doi: 10.3762/bjoc.17.136. PMID: 34476016; PMCID: PMC8381808.
Jung N, Moreth T, Stelzer EHK, Pampaloni F, Windbergs M. Non-invasive analysis of pancreas organoids in synthetic hydrogels defines material-cell interactions and luminal composition. Biomater Sci. 2021 Jul 22; 9(16):5415-5426. doi: 10.1039/d1bm00597.
Kaiser P, Wächter J, Windbergs M. Therapy of infected wounds: overcoming clinical challenges by advanced drug delivery systems. Drug Deliv Transl Res. 2021 Aug;11(4):1545-1567. doi: 10.1007/s13346-021-00932-7. Epub 2021 Feb 20. PMID: 33611768; PMCID: PMC8236057.
