International COST Action Workshop – BM0806  –  WG 4

BioMedChem on Histamine H₄ Receptor

New Compounds for Translational Steps

Date:
Tuesday, October 6, 2009,  09:00 – 16:00
with an envisaged additional WG-4 Meeting on Monday, October 5, 2009, at 18:00 (Room N100 0.15)

Workshop Venue:
60438 Frankfurt am Main, Germany
Johann Wolfgang Goethe-University, Biozentrum,
Max-von-Laue-Str. 9, Lecture room (how to get there)

More photos...

Book of Abstracts: see here

Program: see here

Monday, October 5, 2009

18:00              WG 4 assembly – general meeting: see agenda

Tuesday, October 6, 2009 – Workshop

  9:00              Greetings notes

                        COST chair (E. Tiligada),
                        Vice president of the Goethe-University (M. Schubert-Zsilavecz)
                        Workshop chair (H. Stark)


                        Chair H. Stark

  9:15              Ekaterini Tiligada, University of Athens, GR
             PL-1   PHARMACOLOGY AND THERAPEUTIC PERSPECTIVE OF THE HISTAMINE H₄ RECEPTOR: STATE-OF-
                        THE-ART

  9:45              Madeleine Ennis, Queen’s University of Belfast, UK
             PL-2   H₄ RECEPTORS AND LUNG DISEASE

10:15 – 10:45     Coffee


                        Chair  R. Leurs

10:45              Robert Kiss, Heriot-Watt University, UK
             PL-3   CHEMICAL SPACE OF H₄ LIGANDS EXPLORED BY MOLECULAR MODELING

11:15              Armin Buschauer, University of Regensburg, D
             PL-4   CHANGING HISTAMINE RECEPTOR SELECTIVITY BY BIOISO-STERIC REPLACEMENTS:
                        IMIDAZOLYLALKYLCYANOGUANIDINES AND RELATED COMPOUNDS AS POTENT AND
                        SELECTIVE H₄R AGONISTS

11:45              Anwar Rayan, Al-Quasemi Academic College, IL
             SL-1   THE UTILITY OF INTELLIGENT-LEARNING ENGINE FOR DISCOVERING NOVEL H₄ ANTAGONISTS

12:00              Rogier A. Smits, VU University Amsterdam, NL
             SL-2   LIGAND BASED DESIGN OF NOVEL HISTAMINE H4-RECEPTOR ANTAGONISTS; OPTIMIZATION
                        OF AN ISOQUINOLINE FRAGMENT

12:15 – 13:00     Lunch time


                        Chair E. Tiligada

13:00              Chris de Graaf, VU University Amsterdam, NL
             SL-3   MUCUS, MORPHEUS, PROMETHEUS, PHARMACON: HISTAMINE RECEPTOR SELECTIVITY SWITCHES

13:30              Jose Alfón, Palau Pharma Barcelona, ES
             PL-5   UR-60427: FIRST H₄ RECEPTOR ANTAGONIST IN PRECLINICAL DEVELOPMENT AT PALAU PHARMA

14:00              Roland Seifert, Hannover Medical School, D
             PL-6   MOLECULAR ANALYSIS OF THE HISTAMINE H_⁴-RECEPTOR AND ITS PATHOPHYSIOLOGICAL ROLE
                        IN BRONCHIAL ASTHMA

14:30 – 15:00     Coffee


                        Chair R. Gutzmer

15:00              Heinfried H. Radeke, Goethe-University Frankfurt, D
             PL-7   IMMUNE MODULATION OF DENDRITIC CELLS EMPLOYING SPHINGOLIPID ENZYMES AND GPCR
                        LIGANDS

15:30              Paul L Chazot, Durham University, UK
             PL-8   FURTHER EVIDENCE OF DISTINCT ROLES AND THERAPEUTIC POTENTIAL FOR THE H₃ AND H₄
                        HISTAMINE RECEPTORS IN THE CNS

16:00              Closing remarks

Scientific Committee

Holger Stark (chair)

Madeleine Ennis

Armin Buschauer

Katerina Tiligada

Organizing Committee

Holger Stark (chair)

Aleksandra Zivkovic

Kerstin Sander

Sebastian Barzen

Andreas Lill

Ursula Vierkotten

geändert am 12. Oktober 2009  E-Mail: Webmastersteinhilber@em.uni-frankfurt.de